Human Drug Metabolism: An Introduction By Michael Coleman
Publisher: W.,il..ey; 2 edition 2010 | 360 Pages | ISBN: 0470742178 , 047074216X | PDF | 2 MB
Human Drug Metabolism, An Introduction, Second Edition provides an
accessible introduction to the subject and will be particularly
invaluable to those who already have some understanding of the life
sciences. Completely revised and updated throughout, the new edition
focuses only on essential chemical detail and includes patient case
histories to illustrate the clinical consequences of changes in drug
metabolism and its impact on patient welfare.
After underlining the relationship between efficacy, toxicity and drug
concentration, the book then considers how metabolizing systems operate
and how they impact upon drug concentration, both under drug pressure
and during inhibition. Factors affecting drug metabolism, such as
genetic polymorphisms, age and diet are discussed and how metabolism can
lead to toxicity is explained. The book concludes with the role of drug
metabolism in the commercial development of therapeutic agents as well
as the pharmacology of some illicit drugs.
!!!No Mirrors below, please! Follow Rules!
Welcome to my AH blog!