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    Human Drug Metabolism: An Introduction

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    تاريخ التسجيل : 28/10/2009
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    Human Drug Metabolism: An Introduction

    مُساهمة من طرف d-forum في 30/09/11, 06:45 pm



    Human Drug Metabolism: An Introduction By Michael Coleman
    Publisher: W.,il..ey; 2 edition 2010 | 360 Pages | ISBN: 0470742178 , 047074216X | PDF | 2 MB



    Human Drug Metabolism, An Introduction, Second Edition provides an
    accessible introduction to the subject and will be particularly
    invaluable to those who already have some understanding of the life
    sciences. Completely revised and updated throughout, the new edition
    focuses only on essential chemical detail and includes patient case
    histories to illustrate the clinical consequences of changes in drug
    metabolism and its impact on patient welfare.
    After underlining the relationship between efficacy, toxicity and drug
    concentration, the book then considers how metabolizing systems operate
    and how they impact upon drug concentration, both under drug pressure
    and during inhibition. Factors affecting drug metabolism, such as
    genetic polymorphisms, age and diet are discussed and how metabolism can
    lead to toxicity is explained. The book concludes with the role of drug
    metabolism in the commercial development of therapeutic agents as well
    as the pharmacology of some illicit drugs.


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